Anti-Gresham’s Law: Good information drives out bad

(Good information is in blue, bad information is in Red)

Read an article the other day in ScienceDaily (Faster way to replace bad info in networks) which discusses research published in a recent IEEE/ACM Transactions on Network journal (behind paywall). Luckily there was a pre-print available (Modeling and analysis of conflicting information propagation in a finite time horizon).

The article discusses information epidemics using the analogy of a virus and its antidote. This is where bad information (the virus) and good information (the antidote) circulate within a network of individuals (systems, friend networks, IOT networks, etc). Such bad information could be malware and its good information counterpart could be a system patch to fix the vulnerability. Another example would be an outright lie about some event and it’s counterpart could be the truth about the event.

The analysis in the paper makes some simplifying assumptions. That in a any single individual (network node), both the virus and the antidote cannot co-exist. That is either an individual (node) is infected by the virus or is cured by the antidote or is yet to be infected or cured.

The network is fully connected and complex. That is once an individual in a network is infected, unless an antidote is developed the infection proceeds to infect all individuals in the network. And once an antidote is created it will cure all individuals in a network over time. Some individuals in the network have more connections to other nodes in the network while different individuals have less connections to other nodes in the network.

The network functions in a bi-directional manner. That is any node, lets say RAY, can infect/cure any node it is connected to and conversely any node it is connected to can infect/cure the RAY node.

Gresham’s law, (see Wikipedia article) is a monetary principle which states bad money in circulation drives out good. Where bad money is money that is worth less than the commodity it is backed with and good money is money that’s worth more than the commodity it is backed with. In essence, good money is hoarded and people will preferentially use bad money.

My anti-Gresham’s law is that good information drives out bad. Where good information is the truth about an event, security patches, antidotes to infections, etc. and bad infrormation is falsehoods, malware, biological viruses., etc

The Susceptible Infected-Cured (SIC) model

The paper describes a SIC model that simulates the (virus and antidote) epidemic propagation process or the process whereby virus and its antidote propagates throughout a network. This assumes that once a network node is infected (at time0), during the next interval (time0+1) it infects it’s nearest neighbors (nodes that are directly connected to it) and they in turn infect their nearest neighbors during the following interval (time0+2), etc, until all nodes are infected. Similarly, once a network node is cured it will cure all it’s neighbor nodes during the next interval and these nodes will cure all of their neighbor nodes during the following interval, etc, until all nodes are cured.

What can the SIC model tell us

The model provides calculations to generate a number of statistics, such as half-life time of bad information and extinction time of bad-information. The paper discusses the SIC model across complex (irregular) network topologies as well as completely connected and star topologies and derives formulas for each type of network

In the discussion portion of the paper, the authors indicate that if you are interested in curing a population with bad information it’s best to map out the networks’ topology and focus your curation efforts on those node(s) that lie along the (most) shortest path(s) within a network.

I wrongly thought that the best way to cure a population of nodes would be to cure the nodes with the highest connectivity. While this may work and such nodes, are no doubt along at least one if not all, shortest paths, it may not be the optimum solution to reduce extinction time, especially If there are other nodes on more shortest paths in a network, target these nodes with a cure.

Applying the SIC model to COVID-19

It seems to me that if we were to model the physical social connectivity of individuals in a population (city, town, state, etc.). And we wanted to infect the highest portion of people in the shortest time we would target shortest path individuals to be infected first.

Conversely, if we wanted to slow down the infection rate of COVID-19, it would be extremely important to reduce the physical connectivity of indivduals on the shortest path in a population. Which is why social distancing, at least when broadly applied, works. It’s also why, when infected, self quarantining is the best policy. But if you wished to not apply social distancing in a broad way, perhaps targeting those individuals on the shortest path to practice social distancing could suffice.

However, there are at least two other approaches to using the SIC model to eradicate (extinguish the disease) the fastest:

  1. Now if we were able to produce an antidote, say a vaccine but one which had the property of being infectious (say a less potent strain of the COVID-19 virus). Then targeting this vaccine to those people on the shortest paths in a network would extinguish the pandemic in the shortest time. Please note, that to my knowledge, any vaccine (course), if successful, will eliminate a disease and provide antibodies for any future infections of that disease. So the time when a person is infected with a vaccine strain, is limited and would likely be much shorter than the time soemone is infected with the original disease. And most vaccines are likely to be a weakened version of an original disease may not be as infectious. So in the wild the vaccine and the original disease would compete to infect people.
  2. Another approach to using the SIC model and is to produce a normal (non-transmissible) vaccine and target vaccination to individuals on the shortest paths in a population network. As once vaccinated, these people would no longer be able to infect others and would block any infections to other individuals down network from them. One problem with this approach is if everyone is already infected. Vaccinating anyone will not slow down future infection rates.

There may be other approaches to using SIC to combat COVID-19 than the above but these seem most reasonable to me.

So, health organizations of the world, figure out your populations physical-social connectivity network (perhaps using mobile phone GPS information) and target any cure/vaccination to those individuals on the highest number of shortest paths through your network.

Comments?

Photo Credit(s):

  1. Figure 2 from the Modeling and analysis of conflicting information propagation in a finite time horizon article pre-print
  2. Figure 3 from the Modeling and analysis of conflicting information propagation in a finite time horizon article pre-print
  3. COVID-19 virus micrograph, from USA CDC.

A tale of two countries and how they controlled the Coronavirus

Read an article in IEEE Spectrum last week about Taiwan’s response to COVID-19 (see: Big data helps Taiwan fight Coronavirus) which was reporting on an article in JAMA (see Response to COVID-19 in Taiwan) about Taiwan’s success in controlling the COVID-19 outbreak in their country.

I originally intended this post to be solely about Taiwan’s response to the virus but then thought that it more instructive to compare and contrast Taiwan and South Korea responses to the virus, who both seem to have it under control now (18 Mar 2020).

But first a little about the two countries (source wikipedia: South Korea and Taiwan articles):

Taiwan (TWN) and South Korea (ROK) both enjoy close proximity, trade and travel between their two countries and China

  • South Korea (ROK) has a population of ~50.8M, an area of 38.6K SqMi (100.0K SqKm) and extends about 680 Mi (1100 Km) away from the Asian mainland (China).
  • Taiwan (TWN ) has a population of ~23.4M, an area of 13.8K SqMi (35.8K Sq Km) and is about 110 Mi (180 Km) away from the Asian mainland (China).

COVID-19 disease progression & response in TWN and ROK

There’s lots of information about TWN’s response (see articles mentioned above) to the virus but less so on ROK’s response.

Nonetheless, here’s some highlights of the progression of the pandemic and how they each reacted (source for disease/case progression from : wikipedia Coronavirus timeline Nov’19 to Jan’20, and Coronavirus timeline Feb’20; source for TWN response to virus JAMA article supplement and ROK response to virus Timeline: What the world can learn from South Korea’s COVID-19 response ).

  • Dec. 31, 2019: China Wuhan municipal health announced “urgent notice on the treatment of pneumonia of unknown cause”. Taiwan immediately tightened inbound screening processes. ==> TWN: officials board and inspect passengers for fever or pneumonia symptoms on direct flights from Wuhan
  • Jan. 8, 2020: ROK identifies 1st possible case of the disease in a women who recently returned from China Wuhan province
  • Jan 20: ROK reports 1st laboratory confirmed case ==> TWN: Central Epidemic Command Center activated, activates Level 2 travel alert for Wuhan; ROK CDC starts daily press briefings on disease progress in the nation
  • Jan. 21: TWN identifies 1st laboratory confirmed case ==> TWN: activates Level 3 travel alert for Wuhan
  • Jan 22: ==> TWN: cancels entry permits for 459 tourists from Wuhan set to arrive later in Jan
  • Jan 23: ==> TWN: bans residents from Wuhan, travelers from China required to make online health declaration before entering
  • Jan. 24 ROK reports 2nd laboratory confirmed case ==> TWN bans export of facemasks; ROK, sometime around now the gov’t started tracking confirmed cases using credit card and CCTV data to understand where patients contacted the disease
  • Jan. 25: ==> TWN: tours to china are suspended until Jan 31, activates level 3 travel alert for Hubei Province and Level 2 for rest of China, enacts export ban on surgical masks until Feb 23
  • Jan 26: ==> TWN: all tour groups from Wuhan have to leave,
  • Jan. 27: TWN reports 1st domestic transmission of the disease ==>TWN NHIA and NIA (National health and immigration authorities) integrate (adds all hospital) patients past 14-day travel history to NHIA database, all tour groups from Hubei Province have to leave
  • Jan 28: ==> TWN: activates Level 3 travel alert for all of China except Hong Kong and Macau; ROK requests inspection of all people who have traveled from Wuhan in the past 14 days
  • Jan 29: ==> TWN: institutes electronic monitoring of all quarantined patients via gov’t issued cell phones; ROK about now requests production of massive numbers of WHO approved test kits for the Coronavirus
  • Jan. 30: ROK reports 2 more (4 total) confirmed cases of the disease ==> TWN: tours to or transiting China suspended until Feb 29;
  • Jan 31: ==> TWN: all remaining tour groups from China asked to leave
  • Feb 2 ==> TWN extended school break from Feb 15 to Feb 25,gov’t facilities available for quarantine, soldiers mobilized to man facemask production lines, 60 additional machines installed daily facemask output to reach 10M facemasks a day.
  • Feb 3: ==> TWN: enacts name based rationing system for facemasks, develops mobile phone app to allow public to see pharmacy mask stocks, Wenzhou city Level 2 travel alert; ROK CDC releases enhanced quarantine guidelines to manage the disease outbreak, as of today ROK CDC starts making 2-3 press releases a day on the progress of the disease
  • Feb 5: ==> TWN: Zheijanp province Level 2 travel alert, all cruise ships with suspected cases in past 28 days banned, any cruise ship with previous dockings in China, Hong Kong, or Macau in past 14 days are banned
  • Feb 6:==> TWN: Tours to Hong Kong & Macau suspended until Feb 29, all Chinese nationals banned, all international cruise ship are banned, all contacts from Diamond Princess cruise ship passengers who disembarked on Jan 31 are traced
  • Feb 7: ==> TWN: All foriegn nationals with travel to China, Hong Kong or Macau in the past 14 days are banned, all Foreigners must see an immigration officer,
  • Feb 14:==> TWN: Entry quarantine system launched fill out electronic health declaration for faster entry
  • Feb 16: ==> TWN: NHIA database expanded to cover 30 day travel history for travelers form or transited through China, Hong Kong, Macau, Singapore and Thailand.
  • Feb 18 ==> TWN: all hospitals, clinics and pharmacies have access to patients travel history; ROK most institutions postpone the re-start of school after spring break
  • Feb 19 ==> TWN establishes gov’t policies to disinfect schools and school areas, school buses, high speed rail, railways, tour busses and taxis
  • Feb 20 ==> ROK Daegu requests all individuals to stay home
  • Feb 21 ==> TWN establishes school suspension guidelines based on cases diagnosed in school; ROK Seoul closes all public gatherings and protests
  • Feb 24 ==> TWN, travelers with history of travel to china, from countries with level 1 or 2 travel alerts, and all foreign nationals subject to 14 day quarantine (By this time many countries are in level 1-2-3 travel alert status in TWN)
  • Feb 26 ==> ROK opens drive-thru testing clinics, patients are informed via text messages (3 days later) the results of their tests
  • Mar 3? ==> ROK starts selling facemasks at post offices
  • Mar 5 ==> ROK bans the export of face masks

As of Mar 16, (as reported in Wikipedia), TWN had 67 cases and 1 death; and ROK had 8,326 cases and 75 deaths. As of Mar 13 (as reported is Our world in data article), TWN had tested 16,089 and ROK had tested 248,647 people.

Summary of TWN and ROK responses to the virus

For starters, both TWN and ROK learned valuable lessons from the last infections from China SARS-H1N1 and used those lessons to deal better with COVID-19. Also neither country had any problem accessing credit information, mobile phone location data, CCTV camera or any other electronic information to trace infected people in their respective countries.

If I had to characterize the responses to the virus from the two countries:

  1. TWN was seemingly focused early on reducing infections from outside, controlling & providing face masks to all, and identifying gov’t policies (ceasing public gathering, quarantine and disinfectant procedure) to reduce transmission of the disease. They augmented and promoted the use of public NHIA databases to track recent travel activity and used any information available to monitor the infected and track down anyone they may have contacted. Although TWN has increased testing over time, they did not seem to have much of an emphasis on broad testing. At this point, TWN seems to have the virus under control.
  2. ROK was all about public communications, policies (quarantine and openness), aggressively testing their population and quarantining those that were infected. ROK also tracked the goings on and contacts of anyone that was infected. ROK started early on broadly testing anyone that wanted to be tested. Using test results, infected individuals were asked to quarantine. A reporter I saw talking about ROK mentions 3 T’s: Target, Test, & Trace At this point, ROK seems to have the virus under control.

In addition, Asian countries in general are more prone to use face masks when traveling, which may be somewhat restrict Coronavirus transmission. Although it seems to primarily reduce transmission, most of the public in these countries (now) routinely wear face masks when out and about. And previously they routinely wore face masks when traveling to reduce disease transmission.

Also both countries took the news out of Wuhan China about the extent of the infections, deaths and ease of disease transmission as truthful and acted on this before any significant infections were detected in their respective countries

What the rest of the world can learn from these two countries

What we need to take from TWN a& ROK is that

  1. Face masks and surgical masks are a critical resource during any pandemic. National production needs to be boosted immediately with pricing and distribution controls so that they are not hoarded, nor subject to price gouging. In the USA we have had nothing on this front other than requests to the public to stop hoarding them and the lack of availability to support healthcare workers).
  2. Test kits are also a critical resource during any pandemic. Selection of the test kit, validation and boosting production of test kits needs to be an early and high priority. The USA seems to have fallen down on this job.
  3. Travel restrictions, control and quarantines need to be instituted early on from infected countries. USA did take action to restrict travel and have instituted quarantines on cruise ship passengers and any repatriated nationals from China.
  4. Limited testing can help control the virus as long as it’s properly targeted. Mass, or rather less, targeted testing can also help control the virus as well. In the USA given the lack of test kits, we are limited to targeted testing.
  5. Open, rapid and constant communications can be an important adjunct to help control virus spread. The USA seems to be still working on this. Many states seem to have set up special communications channels to discuss the latest information. But there doesn’t seem to be any ongoing, every day communications effort on behalf of the USA CDC to communicate pandemic status.
  6. When one country reports infections, death and ease of transmission of a disease start to take serious precautions immediately. Disease transmission in our travel intensive world is much too easy and rapid to stop once it takes hold in a nation. Any nation today that starts to encounter and infectious agent with high death rates and seemingly easy transmission must be taken seriously as the start of something much bigger.

Stay safe, be well.

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Comments?

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